• SomePapersAndLinksOnImmunomics

Some example of papers and links covering the area of "immune systems biology"

NOTE!!! This is not a list of papers for the journal club, just a list of resources to have an idea about what each topic is about Good papers will require some selection work... that can be done if this topic is interesting enough! This selection was harvested in pubmed by known authors/project names (I've just read some of these papers. Of most of them I just had a look to the abstract)

Genomic based vaccine design

Two "readings"... the author is De Groot Anne. I guess from a Company called EpiVAX

• (review - no access from Pasteur) http://www.blackwell-synergy.com/doi/abs/10.1046/j.1440-1711.2002.01092.x

• (news)

http://www.nature.com/nbt/journal/v24/n7/full/nbt0706-791.html

Information resources

An example: IMGT (since we are in France...)

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16305737&query_hl=29&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16381979&query_hl=29&itool=pubmed_docsum

Modeling and simulation

Work in this area is articulated, in which modeling is at molecular (signalling), cell-interaction and host-parasite level. Also there are works ranging from purely theooretical to almost "clinial"

• (review) MATHEMATICAL AND COMPUTATIONAL MODELS OF IMMUNE-RECEPTOR SIGNALLING

http://www.nature.com/nri/journal/v4/n6/full/nri1374_fs.html

• Large-scale cellular automata simulations of the immune system response (Bernaschi M, Castiglione F)

http://prola.aps.org/abstract/PRE/v61/i2/p1851_1

• Mutation, fitness, viral diversity, and predictive markers of disease progression in a computational model of HIV type 1 infection.

http://www.liebertonline.com/doi/abs/10.1089%2Faid.2004.20.1314

Host-parasite interaction

This is really just a review on DDT (if the link doesn't work... Host-pathogen systems biology, Forst CV)... just to make the point about this topic. I guess much of the works in this area will not be much computational. But it's an intresting "bio" topic. Since you can study the "mutal understanding" (or cheating ?) of two organisms in evolution. http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T64-4JM3KY9-6&_coverDate=03%2F31%2F2006&_alid=432792800&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=5020&_sort=d&view=c&_acct=C000021652&_version=1&_urlVersion=0&_userid=452888&md5=294edbdcac95f4e4fa17746b0a8a0eb7